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Despite their potency, polyenes, especially AMB, are associated with significant toxicity, including nephrotoxicity, infusion-related reactions (e.g., fever, chills), and venous irritation at the injection site (Deray, 2002

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doi: 10.3389/fnins.2024.1467333 Received 19 July 2024 Accepted 20 September 2024 Published 02 October 2024 Volume 18 - 2024 Edited by Iliya Lefterov, University of Pittsburgh, United States Reviewed by Ankit Seth, Augusta University, United States W